Simple assay for the determination of flumequine and oxolinic acid in fish muscle and skin by HPLC

被引：6

作者：

Hormazábal, V ^{[1
]}

Yndestad, R ^{[1
]}

机构：

[1] Norwegian Sch Vet Sci, Div Food Hyg, Oslo, Norway

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2001年 / 24卷 / 01期

关键词：

D O I：

10.1081/JLC-100000331

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple method for the simultaneous determination of flumequine and oxolinic acid in fish muscle with attached skin is presented. Samples of mass 3.0 g were extracted with NH3 and acetone, acidified, diluted, and analyzed by high-performance liquid chromatography. The limit of quantification was 30 mug/kg for flumequine and 20 mug/kg for oxolinic acid. The recoveries were 75-76% and 79-82% for flumequine and oxolinic acid, respectively.

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页码：109 / 115

页数：7

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