Nitrite conversion by immobilized Nitrobacter agilis cells in an air-lift loop bioreactor cascade: Effects of combined substrate and product inhibition

被引：7

作者：

Bakker, WAM ^{[1
]}

Kers, P ^{[1
]}

Beeftink, HH ^{[1
]}

Tramper, J ^{[1
]}

deGooijer, CD ^{[1
]}

机构：

[1] AGR UNIV WAGENINGEN,DEPT FOOD SCI,FOOD & BIOPROC ENGN GRP,6700 EV WAGENINGEN,NETHERLANDS

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1996年 / 81卷 / 05期

关键词：

Nitrobacter; immobilized cell growth; nitrification; reactor series; substrate inhibition; product inhibition; modeling;

D O I：

10.1016/0922-338X(96)85138-5

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The feasibility of nitrite conversion by immobilized Nitrobacter agilis in an air-lift loop bioreactor cascade was examined. Especially the effects of substrate and product inhibition on the performance of the reactor series were studied. A significant improvement in the degree of substrate conversion was observed with the reactor series as compared to a single vessel at the same overall residence time. The experiments were simulated by a dynamic model that estimates biomass concentration profiles across gel beads in time, incorporating effects of diffusion limitation and substrate and product inhibition. The trend of the model estimates agrees well with the experiments.

引用

页码：390 / 393

页数：4

共 8 条

[1]

BAKKER WAM, 1995, BIOPROCESS ENG, V12, P167, DOI 10.1007/BF01767462

[2]

Barnes D., 1983, BIOL CONTROL NITROGE

[3] Bioreactors in series: An overview of design procedures and practical applications [J].

deGooijer, CD ;

Bakker, WAM ;

Beeftink, HH ;

Tramper, J .

ENZYME AND MICROBIAL TECHNOLOGY, 1996, 18 (03) :202-219

[4] MINIMUM TANK VOLUMES FOR CFST BIOREACTORS IN SERIES [J].

HILL, GA ;

ROBINSON, CW .

CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 1989, 67 (05) :818-824

[5] KINETICS OF NITROBACTER-AGILIS AT EXTREME SUBSTRATE, PRODUCT AND SALT CONCENTRATIONS [J].

HUNIK, JH ;

MEIJER, HJG ;

TRAMPER, J .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1993, 40 (2-3) :442-448

[6] CO-IMMOBILIZED NITROSOMONAS-EUROPAEA AND NITROBACTER-AGILIS CELLS - VALIDATION OF A DYNAMIC-MODEL FOR SIMULTANEOUS SUBSTRATE CONVERSION AND GROWTH IN KAPPA-CARRAGEENAN GEL BEADS [J].

HUNIK, JH ;

BOS, CG ;

VANDENHOOGEN, MP ;

DEGOOIJER, CD ;

TRAMPER, J .

BIOTECHNOLOGY AND BIOENGINEERING, 1994, 43 (11) :1153-1163

[7] PRODUCT FORMATION PATTERNS AND THE PERFORMANCE IMPROVEMENT FOR MULTISTAGE CONTINUOUS STIRRED TANK FERMENTERS [J].

SHIMIZU, K ;

MATSUBARA, M .

CHEMICAL ENGINEERING COMMUNICATIONS, 1987, 52 (1-3) :61-74

[8] GROWTH AND SUBSTRATE CONSUMPTION OF NITROBACTER-AGILIS CELLS IMMOBILIZED IN CARRAGEENAN .2. MODEL EVALUATION [J].

WIJFFELS, RH ;

DEGOOIJER, CD ;

KORTEKAAS, S ;

TRAMPER, J .

BIOTECHNOLOGY AND BIOENGINEERING, 1991, 38 (03) :232-240

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