Efficient synthesis of 2,3-trans-tetrahydropyrans and oxepanes:: Rearrangement-ring expansion of cyclic ethers having a chloromethanesulfonate

被引：29

作者：

Hori, N ^{[1
]}

Nagasawa, K ^{[1
]}

Shimizu, T ^{[1
]}

Nakata, T ^{[1
]}

机构：

[1] Inst Phys & Chem Res, Wako, Saitama 3510198, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 11期

关键词：

rearrangements; tetrahydropyrans; oxepanes; stereocontrol;

D O I：

10.1016/S0040-4039(99)00134-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zn(OAc)(2)-treatment of cyclic ethers having a chloromethanesulfonate as an efficient leaving group on the side chain effected a stereoselective rearrangement reaction to give the ring-expanded ethers, 2,3-trans-tetrahydro-pyrans and oxepanes, in good yield. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：2145 / 2148

页数：4

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