Iridium-catalyzed asymmetric hydrogenation of vinyl ethers

被引：45

作者：

Zhu, Ye ^{[1
]}

Burgess, Kevin ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77841 USA

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2008年 / 350卷 / 7-8期

关键词：

alkenes; asymmetric catalysis; enol ethers; N-heterocyclic carbenes; hydrogenation; iridium;

D O I：

10.1002/adsc.200700546

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A carbene-oxazoline catalyst 1 proved to be an effective catalyst for reduction of an enol ether that the literature suggested could not be hydrogenated effectively by PN-Ir catalysts. Thus, a series of ester and alcohol substrates were hydrogenated using catalyst 1. Good to excellent enantio-selectivities and high conversions were obtained.

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页码：979 / 983

页数：5

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