Enantioselective total synthesis of (+)-duocarmycin A, epi-(+)-duocarmycin A, and their unnatural enantiomers

被引：66

作者：

Boger, DL

McKie, JA

Nishi, T

Ogiku, T

机构：

[1] Department of Chemistry, Scripps Research Institute, San Diego, CA 92037

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 09期

关键词：

D O I：

10.1021/ja953777e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：2301 / 2302

页数：2

共 22 条

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[3] DIASTEREOSELECTIVE DIECKMANN CONDENSATION SUITABLE FOR INTRODUCTION OF THE DUOCARMYCIN A C6 CENTER - DEVELOPMENT OF A DIVERGENT STRATEGY FOR THE TOTAL SYNTHESIS OF DUOCARMYCINS A AND SA
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[4] CC-1065 AND THE DUOCARMYCINS - UNRAVELING THE KEYS TO A NEW CLASS OF NATURALLY DERIVED DNA ALKYLATING-AGENTS
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[5] (+)- AND ENT-(-)-DUOCARMYCIN SA AND (+)- AND ENT-(-)-N-BOC-DSA DNA ALKYLATION PROPERTIES - ALKYLATION SITE MODELS THAT ACCOMMODATE THE OFFSET AT-RICH ADENINE N3 ALKYLATION SELECTIVITY OF THE ENANTIOMERIC AGENTS
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[6] DUOCARMYCIN PYRINDAMYCIN DNA ALKYLATION PROPERTIES AND IDENTIFICATION, SYNTHESIS, AND EVALUATION OF AGENTS INCORPORATING THE PHARMACOPHORE OF THE DUOCARMYCIN PYRINDAMYCIN ALKYLATION SUBUNIT - IDENTIFICATION OF THE CC-1065-DUOCARMYCIN COMMON PHARMACOPHORE
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[7] REGIOCONTROLLED NUCLEOPHILIC-ADDITION TO SELECTIVELY ACTIVATED PARA-QUINONE DIIMINES - ALTERNATIVE PREPARATION OF A KEY INTERMEDIATE EMPLOYED IN THE PREPARATION OF THE CC-1065 LEFT-HAND SUBUNIT
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[8] TOTAL SYNTHESIS AND PRELIMINARY EVALUATION OF (+)-DUOCARMYCIN AND ENT-(-)-DUOCARMYCIN SA
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[9] THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES
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[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1995, 28 (01) : 20 - 29
[10] BOGER DL, 1990, J ORG CHEM, V55, P449

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