THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES

[1] SYNTHESIS AND BIOCHEMICAL EVALUATION OF THE CBI-PDE-I-DIMER, A BENZANNELATED ANALOG OF (+)-CC-106K THAT ALSO PRODUCES DELAYED TOXICITY IN MICE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (14) : 1956 - 1963

[2] A NOVEL PROPERTY OF DUOCARMYCIN AND ITS ANALOGS FOR COVALENT REACTION WITH DNA [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (10) : 4171 - 4177

[3] NEIGHBORING CARBON AND HYDROGEN .51. DIENONES FROM ARO-3 PARTICIPATION - ISOLATION AND BEHAVIOR OF SPIRO(2,5)OCTA-1,4-DIENE-3-ONE [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (05) : 567 - &

[4] Boger D L, 1993, Bioorg Med Chem, V1, P27, DOI 10.1016/S0968-0896(00)82100-8

[5] Boger D L, 1994, Bioorg Med Chem, V2, P115, DOI 10.1016/S0968-0896(00)82007-6

[6] Boger D. L., 1991, CHEMTRACTS ORG CHEM, V4, P329

[7] TOTAL SYNTHESIS OF (+)-DUOCARMYCIN SA [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (25) : 10056 - 10058

[8] CC-1065 PARTIAL STRUCTURES - ENHANCEMENT OF NONCOVALENT AFFINITY FOR DNA MINOR GROOVE BINDING THROUGH INTRODUCTION OF STABILIZING ELECTROSTATIC INTERACTIONS [J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (04) : 1277 - 1284

[9] DEMONSTRATION OF A PRONOUNCED EFFECT OF NONCOVALENT BINDING SELECTIVITY ON THE (+)-CC-1065 DNA ALKYLATION AND IDENTIFICATION OF THE PHARMACOPHORE OF THE ALKYLATION SUBUNIT [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (04) : 1431 - 1435

[10] A DEMONSTRATION OF THE INTRINSIC IMPORTANCE OF STABILIZING HYDROPHOBIC BINDING AND NONCOVALENT VANDERWAALS CONTACTS DOMINANT IN THE NONCOVALENT CC-1065/B-DNA BINDING [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 1990, 73 (01) : 29 - 52

[1] SYNTHESIS AND BIOCHEMICAL EVALUATION OF THE CBI-PDE-I-DIMER, A BENZANNELATED ANALOG OF (+)-CC-106K THAT ALSO PRODUCES DELAYED TOXICITY IN MICE [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (14) : 1956 - 1963

[2] A NOVEL PROPERTY OF DUOCARMYCIN AND ITS ANALOGS FOR COVALENT REACTION WITH DNA [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (10) : 4171 - 4177

[3] NEIGHBORING CARBON AND HYDROGEN .51. DIENONES FROM ARO-3 PARTICIPATION - ISOLATION AND BEHAVIOR OF SPIRO(2,5)OCTA-1,4-DIENE-3-ONE [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (05) : 567 - &

[4] Boger D L, 1993, Bioorg Med Chem, V1, P27, DOI 10.1016/S0968-0896(00)82100-8

[5] Boger D L, 1994, Bioorg Med Chem, V2, P115, DOI 10.1016/S0968-0896(00)82007-6

[6] Boger D. L., 1991, CHEMTRACTS ORG CHEM, V4, P329

[7] TOTAL SYNTHESIS OF (+)-DUOCARMYCIN SA [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (25) : 10056 - 10058

[8] CC-1065 PARTIAL STRUCTURES - ENHANCEMENT OF NONCOVALENT AFFINITY FOR DNA MINOR GROOVE BINDING THROUGH INTRODUCTION OF STABILIZING ELECTROSTATIC INTERACTIONS [J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (04) : 1277 - 1284

[9] DEMONSTRATION OF A PRONOUNCED EFFECT OF NONCOVALENT BINDING SELECTIVITY ON THE (+)-CC-1065 DNA ALKYLATION AND IDENTIFICATION OF THE PHARMACOPHORE OF THE ALKYLATION SUBUNIT [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (04) : 1431 - 1435

[10] A DEMONSTRATION OF THE INTRINSIC IMPORTANCE OF STABILIZING HYDROPHOBIC BINDING AND NONCOVALENT VANDERWAALS CONTACTS DOMINANT IN THE NONCOVALENT CC-1065/B-DNA BINDING [J]. CHEMICO-BIOLOGICAL INTERACTIONS, 1990, 73 (01) : 29 - 52