THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES

被引：137

作者：

BOGER, DL

机构：

[1] Department of Chemistry, Scripps Research Institute, California, 10666 North Torrey Pines Road, La Jolla

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 1995年 / 28卷 / 01期

关键词：

D O I：

10.1021/ar00049a004

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：20 / 29

页数：10

共 96 条

[31] DUOCARMYCIN PYRINDAMYCIN DNA ALKYLATION PROPERTIES AND IDENTIFICATION, SYNTHESIS, AND EVALUATION OF AGENTS INCORPORATING THE PHARMACOPHORE OF THE DUOCARMYCIN PYRINDAMYCIN ALKYLATION SUBUNIT - IDENTIFICATION OF THE CC-1065-DUOCARMYCIN COMMON PHARMACOPHORE
BOGER, DL
ISHIZAKI, T
ZARRINMAYEH, H
MUNK, SA
KITOS, PA
SUNTORNWAT, O
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (24) : 8961 - 8971
[32] CBI-TMI - SYNTHESIS AND EVALUATION OF A KEY ANALOG OF THE DUOCARMYCINS - VALIDATION OF A DIRECT RELATIONSHIP BETWEEN CHEMICAL SOLVOLYTIC STABILITY AND CYTOTOXIC POTENCY AND CONFIRMATION OF THE STRUCTURAL FEATURES RESPONSIBLE FOR THE DISTINGUISHING BEHAVIOR OF ENANTIOMERIC PAIRS OF AGENTS
BOGER, DL
YUN, WY
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (18) : 7996 - 8006
[33] TOTAL SYNTHESIS AND PRELIMINARY EVALUATION OF (+)-DUOCARMYCIN AND ENT-(-)-DUOCARMYCIN SA
BOGER, DL
MACHIYA, K
HERTZOG, DL
KITOS, PA
HOLMES, D
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (20) : 9025 - 9036
[34] DNA ALKYLATION PROPERTIES OF ENHANCED FUNCTIONAL ANALOGS OF CC-1065 INCORPORATING THE 1,2,9,9A-TETRAHYDROCYCLOPROPA[1,2-C]BENZ[1,2-E]INDOL-4-ONE (CBI) ALKYLATION SUBUNIT
BOGER, DL
MUNK, SA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (14) : 5487 - 5496
[35] A POTENT, SIMPLE DERIVATIVE OF AN ANALOG OF THE CC-1065 ALKYLATION SUBUNIT
BOGER, DL
ISHIZAKI, T
ZARRINMAYEH, H
KITOS, PA
SUNTORNWAT, O
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1991, 1 (01) : 55 - 58
[36] AN IMPROVED SYNTHESIS OF 1,2,9,9A-TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL-4-ONE (CBI) - A SIMPLIFIED ANALOG OF THE CC-1065 ALKYLATION SUBUNIT
BOGER, DL
YUN, WY
TEEGARDEN, BR
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (10) : 2873 - 2876
[37] AN ALTERNATIVE AND CONVENIENT STRATEGY FOR GENERATION OF SUBSTANTIAL QUANTITIES OF SINGLY 5'-P-32-END-LABELED DOUBLE-STRANDED DNA FOR BINDING-STUDIES - DEVELOPMENT OF A PROTOCOL FOR EXAMINATION OF FUNCTIONAL FEATURES OF (+)-CC-1065 AND THE DUOCARMYCINS THAT CONTRIBUTE TO THEIR SEQUENCE-SELECTIVE DNA ALKYLATION PROPERTIES
BOGER, DL
MUNK, SA
ZARRINMAYEH, H
ISHIZAKI, T
HAUGHT, J
BINA, M
[J]. TETRAHEDRON, 1991, 47 (14-15) : 2661 - 2682
[38] DNA ALKYLATION PROPERTIES OF THE DUOCARMYCINS - (+)-DUOCARMYCIN-A, EPI-(+)-DUOCARMYCIN-A, ENT-(-)-DUOCARMYCIN-A AND EPI,ENT-(-)-DUOCARMYCIN-A
BOGER, DL
YUN, WY
TERASHIMA, S
FUKUDA, Y
NAKATANI, K
KITOS, PA
JIN, Q
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1992, 2 (07) : 759 - +
[39] FUNCTIONAL ANALOGS OF CC-1065 AND THE DUOCARMYCINS INCORPORATING THE 9A-(CHLOROMETHYL)-1,2,9,9A-TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL-4-ONE (C2BI) ALKYLATION SUBUNIT - SYNTHESIS AND PRELIMINARY DNA ALKYLATION STUDIES
BOGER, DL
PALANKI, MSS
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (24) : 9318 - 9327
[40] TOTAL SYNTHESIS OF (+)-CC-1065 AND ENT-(-)-CC-1065
BOGER, DL
COLEMAN, RS
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (04) : 1321 - 1323

← 1 2 3 4 5 6 7 8 9 10 →