THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES

[11] REVERSIBILITY OF THE DUOCARMYCIN-A AND SA DNA ALKYLATION REACTION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (21) : 9872 - 9873

[12] P-QUINONEMETHIDE ANALOG OF THE CC-1065 AND DUOCARMYCIN ALKYLATION SUBUNITS [J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (17) : 4943 - 4949

[13] (+)-CC-1065 DNA ALKYLATION - KEY STUDIES DEMONSTRATING A NONCOVALENT BINDING SELECTIVITY CONTRIBUTION TO THE ALKYLATION SELECTIVITY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (10) : 3980 - 3983

[14] TOTAL SYNTHESIS OF (+)-CPI-CDPI2 AND (-)-CPI-CDPI2 - (+)-(3BR,4AS)-DEOXY-CC-1065 AND (-)-(3BS,4AR)-DEOXY-CC-1065 [J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (03) : 695 - 698

[15] SYNTHESIS OF N-(TERT-BUTYLOXYCARBONYL)-CBI, CBI, CBI-CDPI1, AND CBI-CDPI2 - ENHANCED FUNCTIONAL ANALOGS OF CC-1065 INCORPORATING THE 1,2,9,9A-TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL-4-ONE (CBI) LEFT-HAND SUBUNIT [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (23) : 5823 - 5832

[16] BOGER DL, 1991, HETEROCYCLES IN BIO-ORGANIC CHEMISTRY, P103

[17] RESOLUTION OF A CBI PRECURSOR AND INCORPORATION INTO THE SYNTHESIS OF (+)-CBI, (+)-CBI-CDPI1, (+)-CBI-CDPI2 - ENHANCED FUNCTIONAL ANALOGS OF (+)-CC-1065 - A CRITICAL-APPRAISAL OF A PROPOSED RELATIONSHIP BETWEEN ELECTROPHILE REACTIVITY, DNA-BINDING PROPERTIES, AND CYTOTOXIC POTENCY [J]. TETRAHEDRON LETTERS, 1990, 31 (06) : 793 - 796

[18] SYNTHESIS AND PRELIMINARY EVALUATION OF AGENTS INCORPORATING THE PHARMACOPHORE OF THE DUOCARMYCIN PYRINDAMYCIN ALKYLATION SUBUNIT - IDENTIFICATION OF THE CC-1065 DUOCARMYCIN COMMON PHARMACOPHORE [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (15) : 4499 - 4502

[19] ISOLATION AND CHARACTERIZATION OF THE DUOCARMYCIN ADENINE DNA ADDUCT [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (17) : 6645 - 6649

[20] ROLE OF THE CC-1065 AND DUOCARMYCIN N-2 SUBSTITUENT - VALIDATION OF A DIRECT RELATIONSHIP BETWEEN SOLVOLYSIS CHEMICAL-STABILITY AND IN-VITRO BIOLOGICAL POTENCY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (12) : 5523 - 5524

[11] REVERSIBILITY OF THE DUOCARMYCIN-A AND SA DNA ALKYLATION REACTION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (21) : 9872 - 9873

[12] P-QUINONEMETHIDE ANALOG OF THE CC-1065 AND DUOCARMYCIN ALKYLATION SUBUNITS [J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (17) : 4943 - 4949

[13] (+)-CC-1065 DNA ALKYLATION - KEY STUDIES DEMONSTRATING A NONCOVALENT BINDING SELECTIVITY CONTRIBUTION TO THE ALKYLATION SELECTIVITY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (10) : 3980 - 3983

[14] TOTAL SYNTHESIS OF (+)-CPI-CDPI2 AND (-)-CPI-CDPI2 - (+)-(3BR,4AS)-DEOXY-CC-1065 AND (-)-(3BS,4AR)-DEOXY-CC-1065 [J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (03) : 695 - 698

[15] SYNTHESIS OF N-(TERT-BUTYLOXYCARBONYL)-CBI, CBI, CBI-CDPI1, AND CBI-CDPI2 - ENHANCED FUNCTIONAL ANALOGS OF CC-1065 INCORPORATING THE 1,2,9,9A-TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL-4-ONE (CBI) LEFT-HAND SUBUNIT [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (23) : 5823 - 5832

[16] BOGER DL, 1991, HETEROCYCLES IN BIO-ORGANIC CHEMISTRY, P103

[17] RESOLUTION OF A CBI PRECURSOR AND INCORPORATION INTO THE SYNTHESIS OF (+)-CBI, (+)-CBI-CDPI1, (+)-CBI-CDPI2 - ENHANCED FUNCTIONAL ANALOGS OF (+)-CC-1065 - A CRITICAL-APPRAISAL OF A PROPOSED RELATIONSHIP BETWEEN ELECTROPHILE REACTIVITY, DNA-BINDING PROPERTIES, AND CYTOTOXIC POTENCY [J]. TETRAHEDRON LETTERS, 1990, 31 (06) : 793 - 796

[18] SYNTHESIS AND PRELIMINARY EVALUATION OF AGENTS INCORPORATING THE PHARMACOPHORE OF THE DUOCARMYCIN PYRINDAMYCIN ALKYLATION SUBUNIT - IDENTIFICATION OF THE CC-1065 DUOCARMYCIN COMMON PHARMACOPHORE [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (15) : 4499 - 4502

[19] ISOLATION AND CHARACTERIZATION OF THE DUOCARMYCIN ADENINE DNA ADDUCT [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (17) : 6645 - 6649

[20] ROLE OF THE CC-1065 AND DUOCARMYCIN N-2 SUBSTITUENT - VALIDATION OF A DIRECT RELATIONSHIP BETWEEN SOLVOLYSIS CHEMICAL-STABILITY AND IN-VITRO BIOLOGICAL POTENCY [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (12) : 5523 - 5524