Plantmetabolomics.org: mass spectrometry-based Arabidopsis metabolomics-database and tools update

被引:17
作者
Bais, Preeti [1 ,2 ]
Moon-Quanbeck, Stephanie M. [3 ]
Nikolau, Basil J. [1 ,3 ]
Dickerson, Julie A. [1 ,2 ,4 ]
机构
[1] Iowa State Univ, Bioinformat & Computat Biol Program, Ames, IA 50011 USA
[2] Iowa State Univ, Dept Elect & Comp Engn, Ames, IA 50011 USA
[3] Iowa State Univ, Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA
[4] Iowa State Univ, Virtual Real Applicat Ctr, Ames, IA 50011 USA
基金
美国国家科学基金会;
关键词
PLANT METABOLOMICS; INFORMATION; BIOLOGY; WEB;
D O I
10.1093/nar/gkr969
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The PlantMetabolomics (PM) database (http://www.plantmetabolomics.org) contains comprehensive targeted and untargeted mass spectrum metabolomics data for Arabidopsis mutants across a variety of metabolomics platforms. The database allows users to generate hypotheses about the changes in metabolism for mutants with genes of unknown function. Version 2.0 of PlantMetabolomics.org currently contains data for 140 mutant lines along with the morphological data. A web-based data analysis wizard allows researchers to select preprocessing and data-mining procedures to discover differences between mutants. This community resource enables researchers to formulate models of the metabolic network of Arabidopsis and enhances the research community's ability to formulate testable hypotheses concerning gene functions. PM features new web-based tools for data-mining analysis, visualization tools and enhanced cross links to other databases. The database is publicly available. PM aims to provide a hypothesis building platform for the researchers interested in any of the mutant lines or metabolites.
引用
收藏
页码:D1216 / D1220
页数:5
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