Observation of a rectangular columnar phase in condensed lamellar cationic lipid-DNA complexes

被引：96

作者：

Artzner, F

Zantl, R

Rapp, G

Radler, JO

机构：

[1] Tech Univ Munich, Lehrstuhl Biophys, D-85748 Garching, Germany

[2] DESY, European Mol Biol Lab, D-22603 Hamburg, Germany

[3] CNRS, URA 1218, Equipe Physicochim Syst Polyphases, F-92296 Chatenay Malabry, France

来源：

PHYSICAL REVIEW LETTERS | 1998年 / 81卷 / 22期

关键词：

D O I：

10.1103/PhysRevLett.81.5015

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We report on a synchrotron x-ray diffraction study of saturated cationic lipid complexed with DNA. In the lipid gel phase L-beta(c), the complexes exhibit Bragg reflections due to lamellar lipid bilayer stacking and three nonintegral peaks in agreement with an intercalated centered rectangular columnar superlattice of DNA. The diffuse broadening of the DNA peaks is caused by in-plane translational disorder of the DNA strands and is approximated by Lorentzians with positional correlation lengths of xi(y) approximate to 250 Angstrom out of plane and xi(x) > 2000 Angstrom in plane. We interpret our results in terms of a system of interacting two-dimensional smectic layers. [S0031-9007(98)07820-X].

引用

页码：5015 / 5018

页数：4

共 16 条

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