Poor outcome of autologous stem cell transplantation for adult T cell leukemia/lymphoma: a case report and review of the literature

被引:81
作者
Tsukasaki, K
Maeda, T
Arimura, K
Taguchi, J
Fukushima, T
Miyazaki, Y
Moriuchi, Y
Kuriyama, K
Yamada, Y
Tomonaga, M
机构
[1] Nagasaki Univ, Sch Med,Inst Atom Dis, Dept Hematol, Mol Med Unit, Nagasaki 852, Japan
[2] Nagasaki Univ, Sch Med, Dept Lab Med, Nagasaki 852, Japan
关键词
ATL; HTLV-1; auto-BMT; auto-PBSCT;
D O I
10.1038/sj.bmt.1701533
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A limited number of patients with adult T cell leukemia/lymphoma (ATL) who received autologous stem cell transplantation (ASCT) have been reported. We report here a case of fatal systemic Candida krusei infection in a female patient with ATL undergoing ASCT, All of the eight patients (including seven patients in the literature) with ATL who received ASCT developed relapse of ATL or death due to ASCT complication, irrespective of subtype or remission state of ATL, source or selection of SCT or conditioning regimen, At present, ASCT appears to provide little benefit for ATL in contrast to that for other types of aggressive non-Hodgkin's lymphoma.
引用
收藏
页码:87 / 89
页数:3
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