Enantioenriched (S)-6,6′-diphenylbinol-Ca:: a novel and efficient chirally modified metal complex for asymmetric epoxidation of α,β-unsaturated enones

被引：45

作者：

Kumaraswamy, G ^{[1
]}

Sastry, MNV

Jena, N

Kumar, KR

Vairamani, M

机构：

[1] Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India

[2] Indian Inst Chem Technol, Natl Ctr Mass Spectrometry, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 23期

关键词：

D O I：

10.1016/j.tetasy.2003.08.022

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A novel enantioenriched-Ca complex was generated using low cost commercially available CaCl, and the potassium salt of (S)-6,6'-diphenylBINOL and its application to alpha,beta-unsaturated enone epoxidation is described. Furthermore the absolute stereochemistry of (S)-6,6'-diphenylBINOL has been corrected and unequivocally established by single crystal X-ray analysis, 500 MHz NMR spectroscopy and mass spectra. The enantiomeric excess (ee) was determined by H-1 NMR spectroscopy of its corresponding MTPA ester and was found to be >98%. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：3797 / 3803

页数：7

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