Dramatic increase of the DNA cleavage activity of Cu(Clip-phen) by fixing the bridging linker on the C3 position of the phenanthroline units

被引：46

作者：

Pitié, M ^{[1
]}

Sudres, B ^{[1
]}

Meunier, B ^{[1
]}

机构：

[1] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 23期

关键词：

D O I：

10.1039/a807807f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of a new ligand with two phenanthrolines bridged on their C-3 carbon by a serinol is reported; Cu(3-Clip-phen) cleaves DNA more efficiently than the parent Cu(2-Clip-phen) bridged on the C-2 carbon.

引用

页码：2597 / 2598

页数：2

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