Towards a molecular approach to gastric cancer management

被引:14
作者
Boussioutas, A
Taupin, D
机构
[1] Canberra Hosp, Gastroenterol Unit, Garran, ACT 2605, Australia
[2] Peter MacCallum Canc Inst, Melbourne, Vic 3000, Australia
关键词
cDNA microarray; expression analysis; gastric cancer; tumour array; tumour marker;
D O I
10.1046/j.1445-5994.2001.00057.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gastric cancer is a leading cause of cancer death worldwide. Most patients with gastric cancer present with locally advanced and incurable disease, and overall survival is poor. Considerable research efforts towards the epidemiology and pathogenesis of gastric cancer have not been translated into treatment success. We discuss current concepts of the pathogenesis of gastric cancer and how recent research advances, in particular global gene expression strategies, may improve this understanding, and suggest a framework wherein these approaches may be used.
引用
收藏
页码:296 / 303
页数:8
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