Neutrophils in asthma-A review

被引：64

作者：

Ciepiela, Olga ^{[1
]}

Ostafin, Magdalena ^{[1
]}

Demkow, Urszula ^{[1
]}

机构：

[1] Med Univ Warsaw, Dept Lab Diagnost & Clin Immunol Dev Age, PL-00576 Warsaw, Poland

来源：

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY | 2015年 / 209卷

关键词：

Neutrophil; Asthma; Interleukin; 8; Neutrophil extracellular trap; PLATELET-ACTIVATING-FACTOR; FC-EPSILON-RI; RESPIRATORY BURST; BLOOD; CHEMOTAXIS; MECHANISMS; RECEPTOR; EXPRESSION; EXPOSURE; RELEASE;

D O I：

10.1016/j.resp.2014.12.004

中图分类号：

Q4 [生理学];

学科分类号：

071003 [生理学];

摘要：

Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling. The review highlights the role of neutrophils in bronchial asthma. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：13 / 16

页数：4

共 37 条

[1]

Regulation of the High Affinity IgE Receptor (FcεRI) in Human Neutrophils: Role of Seasonal Allergen Exposure and Th-2 Cytokines [J].

Alphonse, Martin P. ;

Saffar, Arash S. ;

Shan, Lianyu ;

HayGlass, Kent T. ;

Simons, F. Estelle R. ;

Gounni, Abdelilah S. .

PLOS ONE, 2008, 3 (04)

[2]

Neutrophil Extracellular Trap in Human Diseases [J].

Arazna, Magdalena ;

Pruchniak, Michal P. ;

Zycinska, Katarzyna ;

Demkow, Urszula .

RESPIRATORY REGULATION - THE MOLECULAR APPROACH, 2013, 756 :1-8

[3]

Immunotherapy Reduces Allergen-Mediated CD66b Expression and Myeloperoxidase Levels on Human Neutrophils from Allergic Patients [J].

Aroca, Rocio ;

Chamorro, Cristina ;

Vega, Antonio ;

Ventura, Inmaculada ;

Gomez, Elisa ;

Perez-Cano, Ramon ;

Blanca, Miguel ;

Monteseirin, Javier .

PLOS ONE, 2014, 9 (04)

[4]

Systemic upregulation of neutrophil α-defensins and serine proteases in neutrophilic asthma [J].

Baines, Katherine J. ;

Simpson, Jodie L. ;

Wood, Lisa G. ;

Scott, Rodney J. ;

Gibson, Peter G. .

THORAX, 2011, 66 (11) :942-947

[5]

Molecular mechanisms regulating NETosis in infection and disease [J].

Branzk, Nora ;

Papayannopoulos, Venizelos .

SEMINARS IN IMMUNOPATHOLOGY, 2013, 35 (04) :513-530

[6]

Neutrophil extracellular traps kill bacteria [J].

Brinkmann, V ;

Reichard, U ;

Goosmann, C ;

Fauler, B ;

Uhlemann, Y ;

Weiss, DS ;

Weinrauch, Y ;

Zychlinsky, A .

SCIENCE, 2004, 303 (5663) :1532-1535

[7]

NET balancing: a problem in inflammatory lung diseases [J].

Cheng, Olivia Z. ;

Palaniyar, Nades .

FRONTIERS IN IMMUNOLOGY, 2013, 4

[8]

Cosmi L, 2000, EUR J IMMUNOL, V30, P2972, DOI 10.1002/1521-4141(200010)30:10<2972::AID-IMMU2972>3.0.CO

[9]

2-#

[10]

Advances in neutrophil biology - Clinical implications [J].

Cowburn, Andrew S. ;

Condliffe, Alison M. ;

Farahi, Neda ;

Summers, Charlotte ;

Chilvers, Edwin R. .

CHEST, 2008, 134 (03) :606-612

← 1 2 3 4 →