Screening and comparison of antioxidant activity of solvent extracts of herbal medicines used in Korea

被引:70
作者
Kang, DG
Yun, CK
Lee, HS [1 ]
机构
[1] Wonkwang Univ, Profess Grad Sch Oriental Med, Dept Herbal Resources, Iksan 570749, Jeonbuk, South Korea
[2] Wonkwang Univ, MRRC, Iksan 570749, Jeonbuk, South Korea
[3] Wonkwang Univ, Dept Hlth Adm, Iksan 570749, Jeonbuk, South Korea
关键词
antioxidant; Korean herbal medicines; solvent extracts; screening;
D O I
10.1016/S0378-8741(03)00142-9
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
The hexane. ethylacetate. n-butanol, and water extracts of 10 Korean herbal medicines were screened and compared for their antioxidant activities in a range of lipid peroxidation system using rat brain homogenates, antihemolysis assay of red blood cells, and other in vitro assays to determine their ability to scavenge superoxide and hydroxyl radicals. All of the 10 Korean herbal medicines have potent antioxidant activities. Among the four solvent extracts, the antioxidant activities of more-polar solvent extracts (BuOH and water extracts) were relatively higher than that of non-polar solvent extracts (hexane and EtOAC extracts). These results will be useful to further analyze those herbal medicines that contain the most antioxidant activity in order to identify the active principles. (C) 2003 Elsevier Science Ireland Ltd. All tights reserved.
引用
收藏
页码:231 / 236
页数:6
相关论文
共 20 条
[1]
Bravo L, 1998, NUTR REV, V56, P317, DOI 10.1111/j.1753-4887.1998.tb01670.x
[2]
Antiinflammatory and antioxidant activity of plants used in traditional medicine in Ecuador [J].
de las Heras, B ;
Slowing, K ;
Benedí, J ;
Carretero, E ;
Ortega, T ;
Toledo, C ;
Bermejo, P ;
Iglesias, I ;
Abad, MJ ;
Gómez-Serranillos, P ;
Liso, PA ;
Villar, A ;
Chiriboga, X .
JOURNAL OF ETHNOPHARMACOLOGY, 1998, 61 (02) :161-166
[3]
HALLIWELL B, 1984, LANCET, V1, P1396
[4]
HATANO T, 1989, CHEM PHARM BULL, V37, P2016
[5]
Antioxidant activity of berry and fruit wines and liquors [J].
Heinonen, IM ;
Lehtonen, PJ ;
Hopia, AI .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (01) :25-31
[6]
Hollman P C, 1998, Arch Toxicol Suppl, V20, P237
[7]
Kang DaeGill, 2001, Korean Journal of Pharmacognosy, V32, P253
[8]
Protective effects of the green tea polyphenol (-)-epigallocatechin gallate against hippocampal neuronal damage after transient global ischemia in gerbils [J].
Lee, SR ;
Suh, SI ;
Kim, SP .
NEUROSCIENCE LETTERS, 2000, 287 (03) :191-194
[9]
Water extract of 1:1 mixture of Phellodendron cortex and Aralia cortex has inhibitory effects on oxidative stress in kidney of diabetic rats [J].
Lee, YM ;
Kim, H ;
Hong, EK ;
Kang, BH ;
Kim, SJ .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 73 (03) :429-436
[10]
Antioxidative and free radical scavenging activities of selected medicinal herbs [J].
Liu, F ;
Ng, TB .
LIFE SCIENCES, 2000, 66 (08) :725-735