Norovirus prevalence in 'pathogen negative' gastroenteritis in children from periurban areas in Lima, Peru

被引:10
作者
Rivera, Fulton P. [1 ]
Ochoa, Theresa J. [1 ,2 ]
Ruiz, Joaquim [3 ,4 ]
Medina, Anicia M. [1 ]
Ecker, Lucie [5 ]
Mercado, Erik [1 ]
Gil, Ana I. [5 ]
Huicho, Luis [1 ,6 ,7 ]
Lanata, Claudio F. [5 ,8 ]
机构
[1] Univ Peruana Cayetano Heredia, Lima 31, Peru
[2] Univ Texas Sch Publ Hlth, Houston, TX USA
[3] Hosp Clin Barcelona, Ctr Recerca Salut Int Barcelona, Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain
[4] CIBERESP, Barcelona, Spain
[5] Inst Invest Nutr, Lima 12, Peru
[6] Univ Nacl Mayor San Marcos, Lima 01, Peru
[7] Inst Nacl Salud Nino, Lima 05, Peru
[8] Univ Peruana Ciencias Aplicadas, Lima 33, Peru
基金
美国国家卫生研究院;
关键词
Norovirus; Gastroenteritis; Viral genogroup; Diarrhoea; Children; Peru; PCR;
D O I
10.1016/j.trstmh.2011.08.009
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Norovirus was detected in 17.4% of 224 diarrhoeal samples from children younger than 24 months of age in Lima, in whom all common pathogens had been excluded (pathogen negative). Norovirus was identified more frequently in children older than 12 months of age than in younger children (34% vs 8%, P < 0.001). Among norovirus-positive samples, genogroup II was the predominant group (92%). Compared with rotavirus, norovirus episodes tended to be of shorter duration and less severe. The role of norovirus as a cause of diarrhoea and the ascertainment of its severity in developing countries needs further confirmation by future epidemiological studies. (C) 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:734 / 736
页数:3
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