Filovirus Hemorrhagic Fever Outbreak Case Management: A Review of Current and Future Treatment Options

被引:26
作者
Roddy, Paul [1 ]
Colebunders, Robert [2 ,3 ]
Jeffs, Benjamin [1 ]
Palma, Pedro Pablo [1 ]
Van Herp, Michel [4 ]
Borchert, Matthias [5 ]
机构
[1] Med Sans Frontieres Spain, Barcelona, Spain
[2] Inst Trop Med, B-2000 Antwerp, Belgium
[3] Univ Antwerp, B-2020 Antwerp, Belgium
[4] Med Sans Frontieres Belgium, Brussels, Belgium
[5] Charite, Inst Trop Med & Int Hlth, D-13353 Berlin, Germany
关键词
SANS-FRONTIERES INTERVENTION; EBOLA-VIRUS INFECTION; ACTIVATED PROTEIN-C; POSTEXPOSURE PROTECTION; RNA INTERFERENCE; SEVERE SEPSIS; HEALTH-CARE; MARBURG; ANTISENSE; EPIDEMIC;
D O I
10.1093/infdis/jir297
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe and discuss treatment possibilities, challenges, and potential next steps for FHF outbreak case management. More comprehensive supportive treatment, including vital sign monitoring, intensive care components, and goal-directed interventions may contribute to improved clinical outcome; the feasibility and effectiveness of this more comprehensive supportive treatment should be assessed. Our outlined summary may assist future FHF outbreak case management teams to create collaborative platforms and develop relevant treatment protocols aimed at improving clinical outcome.
引用
收藏
页码:S791 / S795
页数:5
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