A ruthenium-dihydrogen putative intermediate in ketone hydrogenation

被引：100

作者：

Hamilton, RJ ^{[1
]}

Leong, CG ^{[1
]}

Bigam, G ^{[1
]}

Miskolzie, M ^{[1
]}

Bergens, SH ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 12期

关键词：

D O I：

10.1021/ja043339k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The compound fac-[Ru((R)-BINAP)(H)(2-PrOH)3]+ (6) (BINAP = 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl) reacts with (R,R)-dpen (dpen = 1,2-diphenylethylenediamine) under H2 at -60 °C in 2-PrOH-d8/CD2Cl2 to generate the cationic dihydrogen putative intermediate trans-[Ru((R)-BINAP)(H)(η2-H2)((R,R)-dpen)]+ (2′) without H-D exchange between the hydrogen ligands and the solvent. A 1H NMR study concludes that the dihydrogen ligand in 2′ does not protonate 2-PrOH to a catalytically significant extent, and that 2′ requires an added base or hydride source to be an active catalyst. Copyright © 2005 American Chemical Society.

引用

页码：4152 / 4153

页数：2

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