Two triterpene saponins from Achyranthes bidentata

被引：32

作者：

Mitaine-Offer, AC

Marouf, A

Hanquet, B

Birlirakis, N

Lacaille-Dubois, MA

机构：

[1] Univ Bourgogne, Fac Pharm, Unite MIB, Lab Pharmacognosie, F-21079 Dijon, France

[2] Univ Oran, Fac Sci, Dept Biol, Oran, Algeria

[3] Univ Bourgogne, CNRS UMR 5632, Lab Synth & Electrosynth Organomet, F-21004 Dijon, France

[4] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2001年 / 49卷 / 11期

基金：

美国国家科学基金会;

关键词：

Achyranthes bidentata; Amaranthaceae; triterpene-saponin;

D O I：

10.1248/cpb.49.1492

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Bidentatoside II (1) and chikusetsusaponin V methyl ester (2) are two further triterpene saponins isolated from the roots of Achyranthes bidentata. Chemical and homo and heteronuclear two-dimensional (2D) NMR techniques have led to the structural elucidation of 1 which is a new seco-glycoside of oleanolic acid and the full H-1- and C-13-NMR assignments of 2. These compounds did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

引用

页码：1492 / 1494

页数：3

共 9 条

[1] DELETERIOUS EFFECT OF SERUM-PROTEINS ON THE AMPHOTERICIN B-INDUCED POTENTIATION OF CISPLATIN IN HUMAN COLON-CANCER CELLS [J].