Comparative QSAR study of tyrosine kinase inhibitors

被引：45

作者：

Kurup, A ^{[1
]}

Garg, R ^{[1
]}

Hansch, C ^{[1
]}

机构：

[1] Pomona Coll, Dept Chem, Claremont, CA 91711 USA

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 08期

关键词：

D O I：

10.1021/cr010154c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A comparative QSAR study of tyrosine kinase inhibitors was presented. The results and discussions were presented for inhibitors of epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR) and vascular endothelial growth factor receptor (VEGF-R2) tyrosine kinase. The inhibitory activity of the compounds was expressed in molar concentration.

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页码：2573 / 2600

页数：28

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