β-lactam synthetase:: Implications for β-lactamase evolution

被引:37
作者
McNaughton, HJ
Thirkettle, JE
Zhang, ZH
Schofield, CJ
Jensen, SE
Barton, B
Greaves, P
机构
[1] Oxford Ctr Mol Sci, Oxford OX1 3QY, England
[2] Univ Alberta, Edmonton, AB T6G 2E9, Canada
[3] SmithKline Beecham Pharmaceut, Worthing BN14 8QH, W Sussex, England
关键词
D O I
10.1039/a806713i
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A synthetase enzyme catalyses formation of the monocyclic beta-lactam ring during clavulanic acid biosynthesis.
引用
收藏
页码:2325 / 2326
页数:2
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