Reversibly Switching the Function of a Surface between Attacking and Defending against Bacteria

被引:242
作者
Cao, Zhiqiang [1 ]
Mi, Luo [1 ]
Mendiola, Jose [1 ]
Ella-Menye, Jean-Rene [1 ]
Zhang, Lei [1 ]
Xue, Hong [1 ]
Jiang, Shaoyi [1 ]
机构
[1] Univ Washington, Dept Chem Engn, Seattle, WA 98195 USA
关键词
antimicrobial activity; biological activity; surface chemistry; switchable materials; materials science; BIOFILM FORMATION; COATINGS; ADHESION;
D O I
10.1002/anie.201106466
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Attack or defend! A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N-dimethyl-2-morpholinone (CB-Ring) and a zwitterionic carboxy betaine (CB-OH). CB-Ring will kill bacteria upon contact under dry conditions, whereas CB-OH will release the previously attached and dead bacteria and further resist adhesion of bacteria under wet conditions. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2602 / 2605
页数:4
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