Chromatin indexing in Arabidopsis: an epigenomic tale of tails and more

被引:91
作者
Roudier, Francois [1 ]
Teixeira, Felipe Karam [1 ]
Colot, Vincent [1 ]
机构
[1] Ecole Normale Super, CNRS, Dept Biol, UMR8186, Paris, France
关键词
DIRECTED DNA-METHYLATION; GENOME-WIDE; EPIGENETIC MODIFICATIONS; TRANSPOSABLE ELEMENTS; HISTONE MODIFICATION; NATURAL VARIATION; LHP1; PROTEIN; RNA; BINDING; GENES;
D O I
10.1016/j.tig.2009.09.013
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Packaging DNA into chromatin is pivotal for the regulation of genome activity in eukaryotes. This chromatin-level control relies on a range of histone modifications and variants, chromatin-remodeling proteins and DNA methylation in plants and mammals. High-resolution maps have recently been obtained for several chromatin modifications in Arabidopsis, which provide a first glimpse at the organization of plant epigenomes. These maps suggest a pervasive involvement of transcriptional activity in indexing chromatin with reference to the underlying DNA sequence. However, to assess the contribution of chromatin dynamics to plant development and phenotypic plasticity, it will be necessary to shift from a static to a dynamic view of the Arabidopsis epigenome.
引用
收藏
页码:511 / 517
页数:7
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