Synthesis of (2-oxoindolin-3-ylidene)methyl acetates involving a C-H functionalization process

被引：86

作者：

Tang, Shi ^{[1
,3
]}

Peng, Peng ^{[1
]}

Wang, Zhi-Qiang ^{[1
]}

Tang, Bo-Xiao ^{[1
]}

Deng, Chen-Liang ^{[1
]}

Li, Jin-Heng ^{[1
,2
]}

Zhong, Ping ^{[2
]}

Wang, Nai-Xing ^{[3
]}

机构：

[1] Hunan Normal Univ, Key Lab Chem Biol & Trad Chinese Med Res, Changsha 410081, Hunan, Peoples R China

[2] Wenzhou Univ, Coll Chem & Mat Sci, Wenzhou 325035, Peoples R China

[3] Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100080, Peoples R China

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 09期

关键词：

D O I：

10.1021/ol8006315

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A novel palladium-catalyzed oxidative C-H functionalization protocol for the synthesis of (2-oxoindolin-3-ylidene)methyl acetates has been developed. In the presence of Pd(OAC)(2) and Phl(OAC)(2), a variety of N-arylpropiolamides underwent the C-H functionalization reaction with acids to afford the corresponding (E)-(2-oxoindolin-3-ylidene)methyl acetates selectively in moderate to excellent yields.

引用

页码：1875 / 1878

页数：4

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