When Signaling Kinases Meet Histones and Histone Modifiers in the Nucleus

被引：119

作者：

Baek, Sung Hee ^{[1
]}

机构：

[1] Seoul Natl Univ, Creat Res Initiat Ctr Chromatin Dynam, Dept Biol Sci, Seoul 151742, South Korea

来源：

MOLECULAR CELL | 2011年 / 42卷 / 03期

关键词：

NF-KAPPA-B; EZH2 SUPPRESSES METHYLATION; DNA-DAMAGE RESPONSE; H3; PHOSPHORYLATION; AURORA-B; POSTTRANSLATIONAL MODIFICATIONS; TRANSCRIPTIONAL ACTIVATION; GENE-EXPRESSION; CENP-A; CHROMATIN MODIFICATIONS;

D O I：

10.1016/j.molcel.2011.03.022

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Signaling pathways involve cascades of protein phosphorylation and ultimately affect regulation of transcription in the nucleus. However, most of the kinases in these pathways have not been generally considered to directly modulate transcription thus far. Here, recent significant progress in the field elucidating direct modifications of histones and histone modifiers by upstream kinases is summarized, and future directions are discussed.

引用

页码：274 / 284

页数：11

共 101 条

[81] Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 Myoblasts [J].

Takemori, Hiroshi ;

Hashimoto, Yoshiko Katoh ;

Nakae, Jun ;

Olson, Eric N. ;

Okamoto, Mitsuhiro .

ENDOCRINE JOURNAL, 2009, 56 (01) :121-130

[82] Histone variants - ancient wrap artists of the epigenome [J].

Talbert, Paul B. ;

Henikoff, Steven .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2010, 11 (04) :264-275

[83] How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers [J].

Taverna, Sean D. ;

Li, Haitao ;

Ruthenburg, Alexander J. ;

Allis, C. David ;

Patel, Dinshaw J. .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (11) :1025-1040

[84] The Aurora kinase family in cell division and cancer [J].

Vader, Gerben ;

Lens, Susanne M. A. .

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2008, 1786 (01) :60-72

[85] The versatile role of MSKs in transcriptional regulation [J].

Vermeulen, Linda ;

Vanden Berghe, Wim ;

Beck, Ilse M. E. ;

De Bosscher, Karolien ;

Haegeman, Guy .

TRENDS IN BIOCHEMICAL SCIENCES, 2009, 34 (06) :311-318

[86] Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis [J].

Wang, Fangwei ;

Dai, Jun ;

Daum, John R. ;

Niedzialkowska, Ewa ;

Banerjee, Budhaditya ;

Stukenberg, P. Todd ;

Gorbsky, Gary J. ;

Higgins, Jonathan M. G. .

SCIENCE, 2010, 330 (6001) :231-235

[87] The JIL-1 tandem kinase mediates histone H3 phosphorylation and is required for maintenance of chromatin structure in Drosophila [J].

Wang, YM ;

Zhang, WG ;

Jin, Y ;

Johansen, J ;

Johansen, KM .

CELL, 2001, 105 (04) :433-443

[88] Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase [J].

Wang, ZP ;

Bhattacharya, N ;

Mixter, PF ;

Wei, WY ;

Sedivy, J ;

Magnuson, NS .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2002, 1593 (01) :45-55

[89] Histone ubiquitination: Triggering gene activity [J].

Weake, Vikki M. ;

Workman, Jerry L. .

MOLECULAR CELL, 2008, 29 (06) :653-663

[90] Inducible gene expression: diverse regulatory mechanisms [J].

Weake, Vikki M. ;

Workman, Jerry L. .

NATURE REVIEWS GENETICS, 2010, 11 (06) :426-437

← 2 3 4 5 6 7 8 9 10 11 →