Amino alcohol effects on the ruthenium(II)-catalysed asymmetric transfer hydrogenation of ketones in propan-2-ol

被引：300

作者：

Takehara, J

Hashiguchi, S

Fujii, A

Inoue, S

Ikariya, T

Noyori, R

机构：

[1] RES DEV CORP JAPAN,ERATO,MOLEC CATALYSIS PROJECT,TOYOTA 47003,JAPAN

[2] AICHI INST TECHNOL,DEPT APPL CHEM,TOYOTA 47003,JAPAN

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 02期

关键词：

D O I：

10.1039/cc9960000233

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A ruthenium(II) complex generated in situ from [(RuCl2(eta(6)-C(6)Me(6))}(2)], (1S,2S)-2-methylamino-1,2-diphenylethanol and KOH serves as an efficient catalyst for asymmetric transfer hydrogenation of acetophenone derivatives in propan-2-ol to give (S)-enriched alcohols in up to 92% ee and in > 90% yield.

引用

页码：233 / 234

页数：2

共 17 条

[1] ARENE RUTHENIUM(II) COMPLEXES FORMED BY DEHYDROGENATION OF CYCLOHEXADIENES WITH RUTHENIUM(III) TRICHLORIDE
BENNETT, MA
SMITH, AK
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1974, (02): : 233 - 241
[2] HIGHLY FLUXIONAL ARENE CYCLOOCTATETRAENE COMPLEXES OF ZEROVALENT IRON, RUTHENIUM, AND OSMIUM - SINGLE-CRYSTAL X-RAY STUDY OF (CYCLOOCTATETRAENE)(HEXAMETHYLBEZENE)RUTHENIUM(0), RU(ETA-6-HMB)(1-4-ETA-COT)
BENNETT, MA
MATHESON, TW
ROBERTSON, GB
SMITH, AK
TUCKER, PA
[J]. INORGANIC CHEMISTRY, 1980, 19 (04) : 1014 - 1021
[3] ENANTIOSELECTIVE HYDROSILYLATION OF KETONES WITH A CHIRAL TITANOCENE CATALYST
CARTER, MB
SCHIOTT, B
GUTIERREZ, A
BUCHWALD, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (26) : 11667 - 11670
[4] EFFICIENT RUTHENIUM-CATALYZED TRANSFER HYDROGENATION OF KETONES BY PROPAN-2-OL
CHOWDHURY, RL
BACKVALL, JE
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (16) : 1063 - 1064
[5] MEERWEIN-PONNDORF-VERLEY REDUCTIONS AND OPPENAUER OXIDATIONS - AN INTEGRATED APPROACH
DEGRAAUW, CF
PETERS, JA
VANBEKKUM, H
HUSKENS, J
[J]. SYNTHESIS-STUTTGART, 1994, (10): : 1007 - 1017
[6] ASYMMETRIC CATALYTIC REDUCTION OF CARBONYL-COMPOUNDS USING C-2 SYMMETRICAL DIAMINES AS CHIRAL LIGANDS
GAMEZ, P
FACHE, F
LEMAIRE, M
[J]. TETRAHEDRON-ASYMMETRY, 1995, 6 (03) : 705 - 718
[7] ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES USING C2-SYMMETRICAL DIAMINES AS CHIRAL LIGANDS
GAMEZ, P
FACHE, F
MANGENEY, P
LEMAIRE, M
[J]. TETRAHEDRON LETTERS, 1993, 34 (43) : 6897 - 6898
[8] C-2 DIAMINE, PSEUDO-C-2 POLY(AMIDE) AND POLY(UREA) AS CHIRAL INDUCTORS IN ASYMMETRIC CATALYSIS
GAMEZ, P
DUNJIC, B
FACHE, F
LEMAIRE, M
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (12) : 1417 - 1418
[9] GAMEZ P, 1994, B SOC CHIM FR, V131, P600
[10] GENET JP, 1993, SYNLETT, P478

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