Intramolecular alkyne hydroalkoxylation and hydroamination catalyzed by iridium hydrides

被引：224

作者：

Li, XW ^{[1
]}

Chianese, AR ^{[1
]}

Vogel, T ^{[1
]}

Crabtree, RH ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06520 USA

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 24期

关键词：

D O I：

10.1021/ol052186i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Iridium(III) hydrides prove to be air-stable active catalysts for intramolecular hydroalkoxylation and hydroamination of internal alkynes with proximate nucleophiles. The cyclization follows highly selective 6-endo-dig regiochemistry when regioselectivity is an issue.

引用

页码：5437 / 5440

页数：4

共 51 条

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