Daphnane-Type Diterpenoids from Trigonostemon howii

被引：33

作者：

Dong, Shi-Hui ^{[1
]}

Zhang, Chuan-Rui ^{[1
]}

Xu, Cheng-Hui ^{[1
]}

Ding, Jian ^{[1
]}

Yue, Jian-Min ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2011年 / 74卷 / 05期

关键词：

REIDIOIDES; CHINENSIS; REDIOCIDE; APOPTOSIS; ASSAY;

D O I：

10.1021/np200231u

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. Trigohownins A (1) and D (4) exhibited moderate cytotoxic activity against the HL-60 tumor cell line, with IC(50) values of 17.0 and 9.3 mu M, respectively.

引用

页码：1255 / 1261

页数：7

共 19 条

[1] Trigochinins D-I: six new daphnane-type diterpenoids from Trigonostemon chinensis [J].

Chen, Hua-Dong ;

Yang, Sheng-Ping ;

He, Xiu-Feng ;

Liu, Hong-Bing ;

Ding, Jian ;

Yue, Jian-Min .

TETRAHEDRON, 2010, 66 (27-28) :5065-5070

[2] Trigochinins A-C: Three New Daphnane-Type Diterpenes from Trigonostemon chinensis [J].

Chen, Hua-Dong ;

Yang, Sheng-Ping ;

He, Xiu-Feng ;

Ai, Jing ;

Liu, Zhen-Kai ;

Liu, Hong-Bing ;

Geng, Mei-Yu ;

Yue, Jian-Min .

ORGANIC LETTERS, 2010, 12 (06) :1168-1171

[3]

Chen SK., 1997, FLORA CHINA, V44, P162

[4] Rediocides B-E, potent insecticides from Trigonostemon reidioides [J].

Jayasuriya, H ;

Zink, DL ;

Borris, RP ;

Nanakorn, W ;

Beck, HT ;

Balick, MJ ;

Goetz, MA ;

Gregory, L ;

Shoop, WL ;

Singh, SB .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (02) :228-231

[5] Structure and stereochemistry of rediocide A, a highly modified daphnane from Trigonostemon reidioides exhibiting potent insecticidal activity [J].

Jayasuriya, H ;

Zink, DL ;

Singh, SB ;

Borris, RP ;

Nanakorn, W ;

Beck, HT ;

Balick, MJ ;

Goetz, MA ;

Slayton, L ;

Gregory, L ;

Zakson-Aiken, M ;

Shoop, W ;

Singh, SB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (20) :4998-4999

[6] STRUCTURE OF TRIGONOSTEMONE, A NEW PHENANTHRENONE FROM THE THAI PLANT TRIGONOSTEMON-REIDIOIDES [J].

KOKPOL, U ;

THEBPATIPHAT, S ;

BOONYARATAVEJ, S ;

CHEDCHUSKULCAI, V ;

NI, CZ ;

CLARDY, J ;

CHAICHANTIPYUTH, C ;

CHITTAWONG, V ;

MILES, DH .

JOURNAL OF NATURAL PRODUCTS, 1990, 53 (05) :1148-1151

[7] Plant Orthoesters [J].

Liao, Shang-Gao ;

Chen, Hua-Dong ;

Yue, Jian-Min .

CHEMICAL REVIEWS, 2009, 109 (03) :1092-1140

[8] Trigoxyphins A-G: Diterpenes from Trigonostemon xyphophylloides [J].

Lin, Bing-Dong ;

Han, Mei-Ling ;

Ji, Yin-Chun ;

Chen, Hua-Dong ;

Yang, Sheng-Ping ;

Zhang, Sheng ;

Geng, Mei-Yu ;

Yue, Jian-Min .

JOURNAL OF NATURAL PRODUCTS, 2010, 73 (07) :1301-1305

[9] Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase [J].

Lu, HR ;

Zhu, H ;

Huang, M ;

Chen, Y ;

Cai, YJ ;

Miao, ZH ;

Zhang, JS ;

Ding, J .

MOLECULAR PHARMACOLOGY, 2005, 68 (04) :983-994

[10] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS [J].

MOSMANN, T .

JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) :55-63

← 1 2 →