Small animal PET

被引：55

作者：

Myers, R ^{[1
]}

Hume, S ^{[1
]}

机构：

[1] Hammersmith Hosp, Imaging Res Solut Ltd, London W12 0NN, England

来源：

EUROPEAN NEUROPSYCHOPHARMACOLOGY | 2002年 / 12卷 / 06期

关键词：

small animal imaging; positron emission tomography; pharmacokinetics; radioligand; radiotracer;

D O I：

10.1016/S0924-977X(02)00103-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Positron emission tomography (PET) has well-established strengths which are commonly exploited in human clinical research. Not least of these are its dynamic and quantitative capabilities. The recent growth in small animal PET, spurred on by technological developments and an interest in the application of imaging to the field of genomics in mice, has seen impressive improvements in image spatial resolution. The availability of commercial small animal PET scanners has meant a broadening of the user base away from PET development environments and into experimental laboratories. This paper will review these developments and assess the impact on overall data quality. (C) 2002 Published by Elsevier Science B.V.

引用

页码：545 / 555

页数：11

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