Novel streptomycin resistance gene from Mycobacterium fortuitum

被引：18

作者：

Ramon-Garcia, Santiago ^{[1
]}

Otal, Isabel ^{[1
]}

Martin, Carlos ^{[1
]}

Gomez-Lus, Rafael ^{[1
]}

Ainsa, Jose A. ^{[1
]}

机构：

[1] Univ Zaragoza, Fac Med, Dept Microbiol Med Prevent & Salud Publ, E-50009 Zaragoza, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 11期

关键词：

D O I：

10.1128/AAC.00223-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have isolated the aph(3")-Ic gene, encoding an aminoglycoside 3"-O-phosphotransferase [APH(3")-Ic], from a genomic library of an environmental Mycobacterium fortuitum strain, selecting for streptomycin resistance. APH(3")-Ic phosphorylates and inactivates streptomycin. Similar genes have been described in Streptomyces griseus and plasmid RSF1010. It is also present in some M. fortuitum clinical isolates.

引用

页码：3920 / 3922

页数：3

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