Self-regenerating bone implant: Ectopic osteoinduction following intramuscular implantation of a combination of rhBMP-2 atelopeptide Type I collagen and porous hydroxyapatite

被引：20

作者：

Kusumoto, K ^{[1
]}

Bessho, K ^{[1
]}

Fujimura, K ^{[1
]}

Konishi, Y ^{[1
]}

Ogawa, Y ^{[1
]}

Iizuka, T ^{[1
]}

机构：

[1] KYOTO UNIV, FAC MED, DEPT ORAL & MAXILLOFACIAL SURG, KYOTO, JAPAN

来源：

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY | 1996年 / 24卷 / 06期

关键词：

D O I：

10.1016/S1010-5182(96)80037-0

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

A combination of recombinant human bone morphogenetic protein-2 (rhBMP-2), atelopeptide Type I collagen (CL) as a carrier and porous hydroxyapatite (pHAP) was implanted in a calf muscle pouch of the rat. Three rhBMP-2-implanted groups (2, 10 and 50 mu g; each n=5) and the control group (n=5), in which only CL and pHAP were implanted, were established. Three weeks later, the implants were examined.

引用

页码：360 / 365

页数：6

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