MDR-like ABC transporter AtPGP4 is involved in auxin-mediated lateral root and root hair development

被引:177
作者
Santelia, D
Vincenzetti, V
Azzarello, E
Bovet, L
Fukao, Y
Düchtig, P
Mancuso, S
Martinoia, E
Geisler, M [1 ]
机构
[1] Univ Zurich, Zurich Basel Plant Sci Ctr, Inst Plant Biol, CH-8008 Zurich, Switzerland
[2] Univ Bern, Inst Plant Sci, CH-3013 Bern, Switzerland
[3] Ruhr Univ Bochum, Inst Plant Physiol, D-44801 Bochum, Germany
[4] Univ Florence, Dept Hort, I-50019 Sesto Fiorentino, Italy
来源
FEBS LETTERS | 2005年 / 579卷 / 24期
关键词
auxin transport; ABC transporter; MDR; p-glycoprotein; lateral root; root hairs;
D O I
10.1016/j.febslet.2005.08.061
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Previous data have suggested an involvement of MDR/PGP-like ABC transporters in transport of the plant hormone auxin and, recently, AtPGP1 has been demonstrated to catalyze the primary active export of auxin. Here we show that related isoform AtPGP4 is expressed predominantly during early root development. AtPGP4 loss-of-function plants reveal enhanced lateral root initiation and root hair lengths both known to be under the control of auxin. Further, atpgp4 plants show altered sensitivities toward auxin and the auxin transport inhibitor, NPA. Finally, mutant roots reveal elevated free auxin levels and reduced auxin transport capacities. These results together with yeast growth assays suggest a direct involvement of AtPGP4 in auxin transport processes controlling lateral root and root hair development. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:5399 / 5406
页数:8
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