Chemical synthesis of proteins

被引：54

作者：

Borgia, JA ^{[1
]}

Fields, GB

机构：

[1] Florida Atlantic Univ, Dept Chem, Boca Raton, FL 33431 USA

[2] Florida Atlantic Univ, Ctr Mol Biol & Biotechnol, Boca Raton, FL 33431 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2000年 / 18卷 / 06期

关键词：

D O I：

10.1016/S0167-7799(00)01445-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The manipulation of protein structure enables a better understanding of the principles of protein folding, as well as the development of novel therapeutics and drug-delivery vehicles. Chemical synthesis is the most powerful approach for constructing proteins of novel design and structure, allowing for variation of covalent structure without limitations. Here we describe the various chemical methods that are currently used for creating proteins of unique architecture and function.

引用

页码：243 / 251

页数：9

共 112 条

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