Analytical methods for caffeine.

被引：28

作者：

De Maria, Carlos A. B. ^{[1
]}

Moreira, Ricardo F. A. ^{[1
]}

机构：

[1] Univ Fed Estado Rio De Janeiro, Dept Ciencias Fisiol, Inst Biomed, BR-20211040 Rio De Janeiro, Brazil

来源：

QUIMICA NOVA | 2007年 / 30卷 / 01期

关键词：

caffeine; methylxanthines; analytical methods;

D O I：

10.1590/S0100-40422007000100021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gravimetric and Bailey-Andrew methods are tedious and provide inflated results. Spectrofotometry is adequate for caffeine analysis but is lengthy. Gas chromatography also is applied to the caffeine analysis but derivatization is needed. High performance liquid chromatography with ultraviolet detection (HPLC-UV) and reversed phase is simple and rapid for xanthine multianalysis. In HPLC-UV-gel permeation, organic solvents are not used. HPLC-mass spectrometry provides an unequivocal structural identification of xanthines. Capillary electrophoresis is fast and the solvent consumption is smaller than in HPLC. Chemometric methods offer an effective means for chemical data handling in multivariate analysis. Infrared spectroscopy alone or associated with chemometries could predict the caffeine content in a very accurate form. Electroanalytical methods are considered of low cost and easy application in caffeine analysis.

引用

页码：99 / 105

页数：7

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