A study of asymmetric protonation with chiral beta-hydroxy sulfoxides. Asymmetric synthesis of (-)-epibatidine

被引：63

作者：

Kosugi, H

Abe, M

Hatsuda, R

Uda, H

Kato, M

机构：

[1] Inst. for Chemical Reaction Science, Tohoku University, Katahira, Aoba-ku

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 19期

关键词：

D O I：

10.1039/a704779g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The asymmetric synthesis of (-)-epibatidine 1, employing as the key step the asymmetric protonation of the achiral lithum enolate of cyclohexanone derivative 5 with chiral beta-hydroxy sulfoxide 3b, is described.

引用

页码：1857 / 1858

页数：2

共 29 条

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