Comparison of bioactive compounds content, free radical scavenging and anti-acne inducing bacteria activities of extracts from the mangosteen fruit rind at two stages of maturity

被引:114
作者
Pothitirat, Werayut [1 ]
Chomnawang, Mullika Traidej [2 ]
Supabphol, Roongtawan [3 ]
Gritsanapan, Wandee [1 ]
机构
[1] Mahidol Univ, Dept Pharmacognosy, Fac Pharm, Bangkok 10400, Thailand
[2] Mahidol Univ, Dept Microbiol, Fac Pharm, Bangkok 10400, Thailand
[3] Srinakarintarawirot Univ, Dept Physiol, Fac Med, Bangkok, Thailand
关键词
Garcinia mangostana; Antibacterial activity; Antioxidant activity; Acne vulgaris; Propionibacterium acnes; Staphylococcus epidermidis; Mangosteen; GARCINIA-MANGOSTANA; ALPHA-MANGOSTIN; CONSTITUENTS; TANNINS; XANTHONES; APOPTOSIS; HULL;
D O I
10.1016/j.fitote.2009.06.005
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Contents of bioactive components, free radical scavenging and anti-acne producing bacteria activities of young and mature fruit rind extracts of mangosteen were compared. The young fruit rind extract contained significantly higher contents of phenolics and tannins and promoted higher free radical scavenging activity than the mature fruit rind extract, while the later extract contained higher contents of flavonoids and alpha-mangostin xanthone and gave higher anti-acne producing bacteria activity than the young fruit rind extract. Thus, the young and mature stages of mangosteen fruit rind should be beneficial for further development of antioxidant and anti-acne pharmaceutical preparations, respectively. (c) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:442 / 447
页数:6
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