A novel plasma source for sterilization of living tissues

被引:44
作者
Martines, E. [1 ]
Zuin, M. [1 ]
Cavazzana, R. [1 ]
Gazza, E. [1 ]
Serianni, G. [1 ]
Spagnolo, S. [1 ]
Spolaore, M. [1 ]
Leonardi, A. [2 ]
Deligianni, V. [2 ]
Brun, P. [3 ,4 ]
Aragona, M. [3 ]
Castagliuolo, I. [4 ]
Brun, P. [3 ,4 ]
机构
[1] Assoc Euratom ENEA Fus, Consorzio RFX, Padua, Italy
[2] Univ Padua, Ophthalmol Unit, Dept Neurosci, I-35100 Padua, Italy
[3] Univ Padua, Dept Histol Microbiol & Med Biotechnol, Histol Unit, I-35100 Padua, Italy
[4] Univ Padua, Dept Histol Microbiol & Med Biotechnol, Microbiol Unit, I-35100 Padua, Italy
来源
NEW JOURNAL OF PHYSICS | 2009年 / 11卷
关键词
ATMOSPHERIC-PRESSURE; NEEDLE; TEMPERATURE; BACTERIA; CELLS;
D O I
10.1088/1367-2630/11/11/115014
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
A source for the production of low-power plasmas at atmospheric pressure, to be used for the nondamaging sterilization of living tissues, is presented. The source, powered by radiofrequency and working with a helium flow, has a specific configuration, studied to prevent the formation of electric arcs dangerous to living matter. It is capable of killing different types of bacteria with a decimal reduction time of 1-2 min; on the contrary, human cells such as conjunctival fibroblasts were found to be almost unharmed by the plasma. A high concentration of OH radicals, likely to be the origin of the sterilizing effect, is detected through their UV emission lines. The effect of the UV and the OH radicals on the fibroblasts was analysed and no significant effects were detected.
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页数:8
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