Amplifying Different [2]Catenanes in an Aqueous Donor-Acceptor Dynamic Combinatorial Library

被引:65
作者
Au-Yeung, Ho Yu [1 ]
Pantos, G. Dan [1 ]
Sanders, Jeremy K. M. [1 ]
机构
[1] Univ Cambridge, Univ Chem Lab, Cambridge CB2 1EW, England
基金
英国工程与自然科学研究理事会;
关键词
CATENANES; AMPLIFICATION; WATER;
D O I
10.1021/ja906634h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two donor-acceptor [2]catenanes have been synthesized and characterized from a single dynamic combinatorial library in water. One of these catenanes is different from earlier related interlocked molecules in that two donor units stack on each other in an unexpected order. Shifting the equilibrium by choosing the right conditions resulted in a significant increase in the yields of the individual catenanes.
引用
收藏
页码:16030 / +
页数:4
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