Fungal citridone D having a novel phenylfuropyridine skeleton

被引：10

作者：

Fukuda, Takashi

Sakabe, Yasunari

Tomoda, Hiroshi

Omura, Satoshi

机构：

[1] Kitasato Univ, Sch Pharm, Minato Ku, Tokyo 1088641, Japan

[2] Kitasato Univ, Inst Life Sci, Tokyo 1088641, Japan

[3] Kitasato Univ, Grad Sch Infect Control Sci, Tokyo 1088641, Japan

[4] Kitasato Univ, Minato Ku, Tokyo 1088642, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2006年 / 54卷 / 12期

关键词：

citridone; miconazole potentiator; Penicillium sp; phenylfuropyridine; fungal metabolite;

D O I：

10.1248/cpb.54.1659

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Citridone D was isolated from the culture broth of Penicillium sp. FKI-1938 by solvent extraction, silica gel column chromatography and HPLC. The structure of citridone D was elucidated by spectroscopic analysis including NMR analysis. Citridone D was found to have a novel phenylfuropyridine skeleton different from those of other citridones. Citridone D potentiated miconazole activity against Candida albicans.

引用

页码：1659 / 1661

页数：3

共 7 条

[1] Funicone-related compounds, potentiators of antifungal miconazole activity, produced by Talaromyces flavus FKI-0076 [J].