Skeletal absorbed fractions for electrons in the adult male:: Considerations of a revised 50-μm definition of the bone endosteum

被引:26
作者
Bolch, W. E. [1 ]
Shah, A. P. [2 ]
Watchman, C. J. [3 ]
Jokisch, D. W. [4 ]
Patton, P. W. [5 ]
Rajon, D. A. [6 ]
Zankl, M. [7 ]
Petoussi-Henss, N. [7 ]
Eckerman, K. F. [8 ]
机构
[1] Univ Florida, Adv Lab Radiat Dosimetry Studies ALRADS, Dept Nucl & Radiol Engn, Gainesville, FL 32611 USA
[2] Univ Florida, Dept Biomed Engn, Gainesville, FL 32611 USA
[3] Univ Arizona, Dept Radiat Oncol, Tucson, AZ 85721 USA
[4] Francis Marion Univ, Dept Phys & Astron, Florence, SC 29501 USA
[5] Univ Nevada, Dept Hlth Phys, Las Vegas, NV 89154 USA
[6] Univ Florida, Dept Neurosurg, Gainesville, FL 32611 USA
[7] GSF, Natl Res Ctr Environm & Hlth, Inst Radiat Protect, D-85764 Neuherberg, Germany
[8] Oak Ridge Natl Lab, Div Life Sci, Oak Ridge, TN 37831 USA
关键词
D O I
10.1093/rpd/ncm268
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
In 1995, the International Commission on Radiological Protection (ICRP) issued ICRP Publication 70 which provided an extensive update to the physiological and anatomical reference data for the skeleton of adults and children originally issued in ICRP Publication 23. Although ICRP Publication 70 has been a valuable document in the development of reference voxel computational phantoms, additional guidance is needed for dose assessment in the skeletal tissues beyond that given in ICRP Publication 30. In this study, a computed tomography (CT) and micro-CT-based model of the skeletal tissues is presented, which considers (1) a 50-mu m depth in marrow for the osteoprogenitor cells, (2) electron escape from trabecular spongiosa to the surrounding cortical bone, (3) cortical bone to trabecular spongiosa cross-fire for electrons and (4) variations in specific absorbed fraction with changes in bone marrow cellularity for electrons. A representative data set is given for electron dosimetry in the craniofacial bones of the adult male.
引用
收藏
页码:169 / 173
页数:5
相关论文
共 17 条
[11]   Image segmentation of trabecular spongiosa by visual inspection of the gradient magnitude [J].
Rajon, D. A. ;
Pichardo, J. C. ;
Brindle, J. M. ;
Kielar, K. N. ;
Jokisch, D. W. ;
Patton, P. W. ;
Bolch, W. E. .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (18) :4447-4467
[12]  
RICHARDSON RB, 2007, RAD PROT DOSIM
[13]   Accounting for beta-particle energy loss to cortical bone via paired-image radiation transport (PIRT) [J].
Shah, AP ;
Rajon, DA ;
Patton, PW ;
Jokisch, DW ;
Bolch, WE .
MEDICAL PHYSICS, 2005, 32 (05) :1354-1366
[14]  
Shah AP, 2005, J NUCL MED, V46, P344
[15]   Values of "S," ⟨z1⟩, and ⟨z12⟩ for dosimetry using alpha-particle emitters [J].
Stinchcomb, TG ;
Roeske, JC .
MEDICAL PHYSICS, 1999, 26 (09) :1960-1971
[16]   Spatial distribution of blood vessels and CD34+ hematopoietic stem and progenitor cells within the marrow cavities of human cancellous bone [J].
Watchman, Christopher J. ;
Bourke, Vincent A. ;
Lyon, Jared R. ;
Knowlton, Andrea E. ;
Butler, Samantha L. ;
Grier, David D. ;
Wingard, John R. ;
Braylan, Raul C. ;
Bolch, Wesley E. .
JOURNAL OF NUCLEAR MEDICINE, 2007, 48 (04) :645-654
[17]   Voxel-based models representing the male and female ICRP reference adult - The skeleton [J].
Zankl, M. ;
Eckerman, K. E. ;
Bolch, W. E. .
RADIATION PROTECTION DOSIMETRY, 2007, 127 (1-4) :174-186