Putting tumours in context

被引：1631

作者：

Bissell, MJ ^{[1
]}

Radisky, D ^{[1
]}

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA

来源：

NATURE REVIEWS CANCER | 2001年 / 1卷 / 01期

关键词：

D O I：

10.1038/35094059

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The interactions between cancer cells and their micro- and macroenvironment create a context that promotes tumour growth and protects it from immune attack. The functional association of cancer cells with their surrounding tissues forms a new 'organ' that changes as malignancy progresses. Investigation of this process might provide new insights into the mechanisms of tumorigenesis and could also lead to new therapeutic targets.

引用

页码：46 / 54

页数：9

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