Protection against UVB irradiation by natural filters extracted from lichens

被引:78
作者
Rancan, F
Rosan, S
Boehm, K
Fernández, E
Hidalgo, ME
Quihot, W
Rubio, C
Boehm, F
Piazena, H
Oltmanns, U
机构
[1] Meoclin Berlin, D-10117 Berlin, Germany
[2] Humboldt Univ, Dept Dermatol, Charite, D-10117 Berlin, Germany
[3] Humboldt Univ, Dept Pulmonol, D-10117 Berlin, Germany
[4] Univ Valparaiso, Chem & Pharm Sch, Valparaiso, Chile
关键词
lichens; natural sunscreen; UV-light filters; UV protection factor; photostability;
D O I
10.1016/S1011-1344(02)00362-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Natural substances extracted from lichens and boldo tree were tested in vivo and in vitro as possible UV-light filters. The protection factors were compared with that found for the references: Nivea sun Spray LSF 5, octylmethoxycinnamate (OMC) and 4-tert, -butyl-4'-methoxy dibenzoylmethane (BM-DBM). The stability of the single compounds was studied through UV-Vis spectroscopy. Usnic acid resulted to be the best UVB filter, with an in vivo protection factor similar to Nivea sun Spray LSF 5. Most of the single compounds studied in vitro resulted to have higher or similar filtering power than octylmethoxycinnamate. The protection factors as well as the good UV-light absorption of their photo-products suggest that these natural substances may be useful as new filters in sun-screen preparations. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:133 / 139
页数:7
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