Adhesion proteins of Mycoplasma pneumoniae

被引：36

作者：

Chaudhry, Rama ^{[1
]}

Varshney, Avanish Kumar

Malhotra, Pawan

机构：

[1] All India Inst Med Sci, Dept Microbiol, New Delhi 110029, India

[2] Int Ctr Genet Engn & Biotechnol, New Delhi, India

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2007年 / 12卷

关键词：

adhesin; protein; Mycoplasma pneumoniae; infection; review;

D O I：

10.2741/2093

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mycoplasmas are unique cell wall deficient, cholesterol requiring, highly pleomorphic bacteria that possess very small genome. M. pneumoniae is an important human pathogen that possesses specialized tip organelle to mediate cytadherence. It is a complex multifactorial process requiring a group of mycoplasma proteins such as P1, P30, P116 and HMW1-3. Expression of major mycoplasma adhesin proteins in heterologous expression systems provides an opportunity to study the role(s) of these proteins in pathogenicity and helps to develop diagnostic reagents. In this review we highlight the role (s) of various cytadhesin proteins of M. pneumoniae.

引用

页码：690 / 699

页数：10

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