Cross-coupling approach towards dynemicin analogs without the nitrogen

被引：13

作者：

Bosse, F ^{[1
]}

Tunoori, AR ^{[1
]}

Maier, ME ^{[1
]}

机构：

[1] UNIV HALLE WITTENBERG,FACHBEREICH CHEM,INST ORGAN CHEM,D-06120 HALLE,GERMANY

来源：

TETRAHEDRON | 1997年 / 53卷 / 27期

关键词：

D O I：

10.1016/S0040-4020(97)00616-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Utilizing a cross-coupling reaction between the arylstannane 5 and the iodoenone 7, the arylcyclohexenone 8 was prepared. This compound was then transformed into the enediyne aldehydes 16a,b. Treatment of 16a with cat. amounts of TBAF gave rise to the macrocyclic dynemicin analog 17a. This was converted to the phenolic enediyne 18. (C) 1997 Elsevier Science Ltd.

引用

页码：9159 / 9168

页数：10

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