A simple asymmetric organocatalytic approach to optically active cyclohexenones

被引：181

作者：

Carlone, Armando ^{[1
]}

Marigo, Mauro ^{[1
]}

North, Chris ^{[1
]}

Landa, Aitor ^{[1
]}

Jorgensen, Karl Anker ^{[1
]}

机构：

[1] Aarhus Univ, Danish Natl Res Fdn, Ctr Catalysis, Dept Chem, DK-8000 Aarhus C, Denmark

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 47期

关键词：

D O I：

10.1039/b611366d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Optically active 2,5-disubstituted-cyclohexen-2-one derivatives have been prepared in a one-pot process consisting of five reaction steps: an organocatalytic asymmetric conjugated addition of beta-ketoesters to alpha,beta-unsaturated aldehydes that proceeds in aqueous solutions or under solvent-free conditions has been implemented in a multi-step process.

引用

页码：4928 / 4930

页数：3

共 54 条

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