Chitosan-Gated Magnetic-Responsive Nanocarrier for Dual-Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy

被引：44

作者：

Wang, Hui ^{[1
]}

Mu, Qingxin ^{[1
]}

Revia, Richard ^{[1
]}

Wang, Kui ^{[1
]}

Zhou, Xuezhe ^{[1
]}

Pauzauskie, Peter J. ^{[1
,2
]}

Zhou, Shuiqin ^{[3
]}

Zhang, Miqin ^{[1
]}

机构：

[1] Univ Washington, Dept Mat Sci & Engn, Seattle, WA 98195 USA

[2] Pacific Northwest Natl Lab, Fundamental & Computat Sci Directorate, Richland, WA 99354 USA

[3] CUNY, Dept Chem, Coll Staten Isl, Staten Isl, NY 10314 USA

来源：

ADVANCED HEALTHCARE MATERIALS | 2017年 / 6卷 / 06期

关键词：

MESOPOROUS SILICA NANOPARTICLES; CARBON DOTS; ANTICANCER DRUG; DELIVERY; CARRIER; HYPERTHERMIA; NANOCAPSULES; CHEMISTRY; DRIVEN; OXIDE;

D O I：

10.1002/adhm.201601080

中图分类号：

R318 [生物医学工程];

学科分类号：

100103 [病原生物学];

摘要：

A dual-layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on-demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic-thermal and chemotherapy.

引用

页数：11

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