Recent updates on onchocerciasis: Diagnosis and treatment

被引：75

作者：

Udall, Don N. ^{[1
]}

机构：

[1] Univ Calif San Diego, Dermatol Clin Trials Unit, La Jolla, CA 92037 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2007年 / 44卷 / 01期

关键词：

D O I：

10.1086/509325

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recent progress in onchocerciasis research has led to improved understanding of the immunopathology of Onchocerca volvulus, as well as improvements in diagnosis and treatment of this morbid disease. This article reviews the recent literature, highlighting breakthroughs in sensitive means of antigen testing and an unusual new approach to therapy that targets an endosymbiotic bacterium required for filarial worm fecundity.

引用

页码：53 / 60

页数：8

共 76 条

[21] The antiparasitic moxidectin: Safety, tolerability, and pharmacokinetics in humans [J].

Cotreau, MM ;

Warren, S ;

Ryan, JL ;

Fleckenstein, L ;

Vanapalli, SR ;

Brown, KR ;

Rock, D ;

Chen, CY ;

Schwertschlag, US .

JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 43 (10) :1108-1115

[22]

DUKE BOL, 1993, TROP MED PARASITOL, V44, P61

[23] Evidence for macrofilaricidal activity of ivermectin against female Onchocerca volvulus:: further analysis of a clinical trial in the Republic of Cameroon indicating two distinct killing mechanisms [J].

Duke, BOL .

PARASITOLOGY, 2005, 130 :447-453

[24] Misidentification of Onchocerca volvulus as guinea worm [J].

Eberhard, ML ;

Melemoko, G ;

Zee, AK ;

Weisskopf, MG ;

Ruiz-Tiben, E .

ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 2001, 95 (08) :821-826

[25] Onchocerciasis: a potential risk factor for glaucoma [J].

Egbert, PR ;

Jacobson, DW ;

Fiadoyor, S ;

Dadzie, P ;

Ellingson, KD .

BRITISH JOURNAL OF OPHTHALMOLOGY, 2005, 89 (07) :796-798

[26] A comparison of genetic polymorphism in populations of Onchocerca volvulus from untreated- and ivermectin-treated patients [J].

Eng, JKL ;

Prichard, RK .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2005, 142 (02) :193-202

[27] A randomized, double-blind, controlled trial of the effects of ivermectin at normal and high doses, given annually or three-monthly, against Onchocerca volvulus:: ophthalmological results [J].

Fobi, G ;

Gardon, J ;

Kamgno, J ;

Aimard-Favennec, L ;

Lafleur, C ;

Gardon-Wendel, N ;

Duke, BOL ;

Boussinesq, M .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2005, 99 (04) :279-289

[28]

FORGIONE MA, 2002, ONCHOCERCIASIS

[29] Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro [J].

Gopinath, R ;

Ostrowski, M ;

Justement, SJ ;

Fauci, AS ;

Nutman, TB .

JOURNAL OF INFECTIOUS DISEASES, 2000, 182 (06) :1804-1808

[30] What is the real target for ivermectin resistance selection in Onchocerca volvulus? [J].

Grant, W .

PARASITOLOGY TODAY, 2000, 16 (11) :458-459

← 1 2 3 4 5 6 7 8 →