Highly efficient synthesis of thioesters in water

被引：14

作者：

Boeini, Hassan Zali ^{[1
]}

Kashan, Maryam Eshghi ^{[1
]}

机构：

[1] Univ Isfahan, Dept Chem, Esfahan, Iran

来源：

GREEN CHEMISTRY | 2009年 / 11卷 / 12期

关键词：

COENZYME-A; ACYLATION; ALDEHYDES; VERSATILE; ALCOHOLS; ESTERS; ALDOL; BIOSYNTHESIS; REACTIVITY; CATALYSTS;

D O I：

10.1039/b916852d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thioesters were efficiently prepared via the direct reaction of tertiary thioamides and alkyl halides in water, and in the presence of catalytic amounts of NaI, hexadecyltrimethylammonium bromide (HTAB), and 1,4-diazabicyclo[2.2.2] octane (DABCO). Hence, thioamides smoothly undergo an S-alkylation with alkyl halides in aqueous media following by hydrolysis to afford the corresponding thioesters in very good to excellent yields.

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页码：1987 / 1991

页数：5

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