Complete Nucleotide Sequence of pCTX-M360, an Intermediate Plasmid between pEL60 and pCTX-M3, from a Multidrug-Resistant Klebsiella pneumoniae Strain Isolated in China

被引：24

作者：

Zhu, Wen-han ^{[1
,2
]}

Luo, Lan ^{[3
]}

Wang, Jia-yi ^{[1
,2
]}

Zhuang, Xiao-hong ^{[1
,2
]}

Zhong, Ling ^{[4
]}

Liao, Kang ^{[3
]}

Zeng, Yan ^{[3
]}

Lu, Yong-jun ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sch Life Sci, Dept Biochem, Guangzhou 510275, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R China

[3] Sun Yat Sen Univ, Affiliated Hosp 1, Guangzhou 510275, Guangdong, Peoples R China

[4] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510275, Guangdong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 12期

基金：

中国国家自然科学基金;

关键词：

SPECTRUM BETA-LACTAMASES; CTX-M; KLUYVERA-ASCORBATA; ENZYMES; SPREAD; ESBLS; CTX-M-3; POLAND;

D O I：

10.1128/AAC.00032-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this work we report the characterization of plasmid pCTX-M360, isolated from a Klebsiella pneumoniae strain from China and encoding the CTX-M-3 extended-spectrum beta-lactamase. Sequence analysis of pCTX-M360 revealed extensive similarity with pEL60 and pCTX-M3, two other enterobacterial plasmids of the IncL/M incompatibility group. Compared to pEL60, pCTX-M360 contains several insertions but lacks most of a 27-kb insert found in pCTX-M3, suggesting that it could be an evolutionary intermediate between pEL60 and pCTX-M3.

引用

页码：5291 / 5293

页数：3

共 17 条

[1] Countrywide spread of CTX-M-3 extended-spectrum β-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland
Baraniak, A
Fiett, J
Sulikowska, A
Hryniewicz, W
Gniadkowski, M
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (01) : 151 - 159
[2] Two different extended-spectrum β-lactamases (ESBLs) in one of the first ESBL-producing salmonella isolates in Poland
Baraniak, A
Sadowy, E
Hryniewicz, W
Gniadkowski, M
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (03) : 1095 - 1097
[3] Growing group of extended-spectrum β-lactamases:: The CTX-M enzymes
Bonnet, R
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (01) : 1 - 14
[4] Characterization of a chromosomally encoded extended-spectrum class A β-lactamase from Kluyvera cryocrescens
Decousser, JW
Poirel, L
Nordmann, P
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (12) : 3595 - 3598
[5] Comparative analysis of IncHI2 plasmids carrying blaCTX-M-2 or blaCTX-M-9 from Escherichia coli and salmonella enterica strains isolated from poultry and humans
Fernandez, Aurora Garcia
Cloeckaert, Axel
Bertini, Alessia
Praud, Karine
Doublet, Benoit
Weill, Francois-Xavier
Carattolil, Alessandra
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (11) : 4177 - 4180
[6] Prevalence and Genetic Characterization of blaCTX-M Among Klebsiella pneumoniae Isolates Collected in an Intensive Care Unit in Brazil
Filho, J. R. Do Carmo
Silva, R. M.
Castanheira, M.
Tognim, M. C. B.
Gales, A. C.
Sader, H. S.
[J]. JOURNAL OF CHEMOTHERAPY, 2008, 20 (05) : 600 - 603
[7] Nucleotide sequences, genetic organization, and distribution of pEU30 and pEL60 from Enwinia amylovora
Foster, GC
McGhee, GC
Jones, AL
Sundin, GW
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 70 (12) : 7539 - 7544
[8] Complete nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum β-lactamase gene blaCTX-M-3
Golebiewski, M.
Kern-Zdanowicz, I.
Zienkiewicz, M.
Adamczyk, M.
Zylinska, J.
Baraniak, A.
Gniadkowski, M.
Bardowski, J.
Ceglowski, P.
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (11) : 3789 - 3795
[9] β-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types
Humeniuk, C
Arlet, G
Gautier, V
Grimont, P
Labia, R
Philippon, A
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (09) : 3045 - 3049
[10] CTX-M: changing the face of ESBLs in Europe
Livermore, David M.
Canton, Rafael
Gniadkowski, Marek
Nordmann, Patrice
Rossolini, Gian Maria
Arlet, Guillaume
Ayala, Juan
Coque, Teresa M.
Kern-Zdanowicz, Izabela
Luzzaro, Francesco
Poirel, Laurent
Woodford, Neil
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2007, 59 (02) : 165 - 174

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